Overview

This is a fixture that dates back to 1960, when the New England Patriots were known as the Boston Patriots. The Buffalo Bills won the first game – they clinched a 13-0 victory. Since then, this has become a major NFL rivalry with both competing in the AFC East. But the head-to-head was one-sided while Tom Brady was playing for the Pats. He enjoyed a 32-3 winning record against the Bills during his New England career. Plenty of high-profile stars have played for both franchises. These include Brandon Spikes, Chris Hogan, and Stephon Gilmore.